{"id":2628,"date":"2025-01-14T16:11:14","date_gmt":"2025-01-14T13:11:14","guid":{"rendered":"https:\/\/veteriner.cc\/?p=2628"},"modified":"2025-01-14T16:11:14","modified_gmt":"2025-01-14T13:11:14","slug":"koyun-keci-cicek-hastaligi-sheep-pox-sisease","status":"publish","type":"post","link":"https:\/\/veteriner.cc\/?p=2628","title":{"rendered":"KOYUN – KE\u00c7\u0130 \u00c7\u0130\u00c7EK HASTALI\u011eI (SHEEP POX S\u0130SEASE)"},"content":{"rendered":"\n

Koyun-ke\u00e7i \u00e7i\u00e7e\u011fi, koyun ve ke\u00e7ilerde ate\u015f, \u00f6zelikle deri ve akci\u011ferlerde olmak \u00fczere hayvanlar\u0131n b\u00fct\u00fcn v\u00fccuduna yay\u0131lan, vezik\u00fcllerle (i\u00e7i s\u0131v\u0131 dolu kesecikler) karakterize \u00f6ld\u00fcr\u00fcc\u00fc bir viral bir hastal\u0131\u011f\u0131d\u0131r.<\/p>\n\n\n

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\"\"<\/a><\/figure>\n<\/div>\n\n\n

 Etiyolojisi:<\/strong><\/p>\n\n\n\n

Hastal\u0131\u011f\u0131n etkeni bir vir\u00fcst\u00fcr. Vir\u00fcs Poxviridae familyas\u0131 Capripoxvirus genusunun bir \u00fcyesidir.Virus, \u00e7\u00fcr\u00fcmeye, asit ve alkali ko\u015fullara diren\u00e7lidir. Kuru kabuklarda y\u0131llarca, y\u00fcnde 2 ay ve bula\u015f\u0131k y\u00fczeylerde 6 ay canl\u0131 kalabilir. \u0130odofor ve klorin dioksit gibi genel dezenfektanlara duyarl\u0131d\u0131r. Etken direkt olarak g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131na maruz kald\u0131\u011f\u0131nda k\u0131sa zamanda zarars\u0131z hale gelmektedir. Bu nedenle hastal\u0131k \u00e7\u0131kan yerlerde a\u015f\u0131lama yap\u0131laca\u011f\u0131 zaman kullan\u0131lan a\u015f\u0131lar\u0131n uygulama a\u015famas\u0131nda g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131ndan korunmas\u0131 \u00f6nemlidir. Vir\u00fcs\u00fcn \u00e7evre ko\u015fullar\u0131na dayan\u0131kl\u0131 olmas\u0131 hastal\u0131kla m\u00fccadelede zorluklar olu\u015fturmaktad\u0131r.<\/p>\n\n\n\n

Klinik bulgular, Belirtiler<\/strong>:<\/p>\n\n\n\n

   Koyun-Ke\u00e7i \u00c7i\u00e7ek, deride pap\u00fclo-vezik\u00fcler ya da nod\u00fcler formda g\u00f6z\u00fckebilen akut ya da kronik seyirli viral bir hastal\u0131kt\u0131r. Hastal\u0131\u011f\u0131n \u015fiddeti, virus su\u015funa, hayvan\u0131n ya\u015f ve \u0131rk\u0131na ba\u011fl\u0131 olarak de\u011fi\u015fir. 1 ayl\u0131\u011f\u0131n alt\u0131ndaki kuzu ve o\u011flaklar \u015fiddetli generalize hastal\u0131ktan \u00f6l\u00fcrler. Ya\u015fl\u0131 hayvanlarda klinik bulgular daha az \u015fiddetli ve \u00f6l\u00fcm nadirdir. \u00d6l\u00fcm, \u00e7o\u011funlukla i\u00e7 organlar\u0131n ve \u00f6zellikle akci\u011ferlerin enfeksiyonunu izler. Yeti\u015fkinlerde morbidite, birka\u00e7 subklinik enfeksiyon ile birlikte yakla\u015f\u0131k 80%, mortalite yakla\u015f\u0131k 50%\u2019dir. Bir ayl\u0131\u011f\u0131n alt\u0131ndaki duyarl\u0131 kuzu ve o\u011flaklarda ise morbidite 100%\u2019e ula\u015fabilir and mortalite 95% kadar y\u00fcksek olabilir. E\u015flik eden PPR enfeksiyonunun varl\u0131\u011f\u0131nda mortalite oran\u0131, 50%-90%\u2019lara kadar \u00e7\u0131kar.Ayr\u0131ca k\u00f6t\u00fc beslenme, a\u011f\u0131r parazitizm ve \u015fiddetli iklimsel ko\u015fullar da mortaliteyi artt\u0131ran fakt\u00f6rlerdir.<\/p>\n\n\n\n

Klinik olaylar, hafiften \u015fiddetliye kadar de\u011fi\u015fir. Hastal\u0131\u011f\u0131n ink\u00fcbasyon periyodu, enfekte ve duyarl\u0131 hayvan aras\u0131ndaki temas\u0131 takiben 8-13 g\u00fcnd\u00fcr. Ancak insektler taraf\u0131ndan mekanik bula\u015fmay\u0131 ya da deneysel intradermal inok\u00fclasyonu takiben 4 g\u00fcn kadar k\u0131sa olabilir. Baz\u0131 Avrupa koyun \u0131rklar\u0131, deri lezyonlar\u0131 geli\u015fmeden \u00f6nce akut enfeksiyon sonucu \u00f6l\u00fcrler. \u0130lk bulgular, ate\u015f, depresyon, konjunktivitis, lakrimasyon ve rinitistir. Bu bulgular\u0131n g\u00f6r\u00fclmesini takiben 2-5 g\u00fcn i\u00e7inde perineum, inguinal b\u00f6lge, skrotum, meme, koltuk altlar\u0131 ve burun ucu gibi derinin pigmentsiz ve y\u00fcns\u00fcz k\u0131s\u0131mlar\u0131nda daha kolay se\u00e7ilebilen deri lezyonlar\u0131 geli\u015fir.<\/p>\n\n\n

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\"\"<\/a><\/figure>\n<\/div>\n\n\n

Kar\u0131\u015ft\u0131\u011f\u0131 Hastal\u0131klar:<\/strong><\/p>\n\n\n\n

  Mavi dil, PPR, Bula\u015f\u0131c\u0131 ektima, paraziter pn\u00f6moni,  uyuz, b\u00f6cek sinek \u0131s\u0131rmalar\u0131, kaze\u00f6z lenfadenitis, dermatofilozis gibi hastal\u0131klardan ay\u0131rt edilmesi gerekir.<\/p>\n\n\n\n

 Te\u015fhis:<\/strong><\/p>\n\n\n\n

    Beden \u0131s\u0131s\u0131 art\u0131\u015f\u0131 ile birlikte v\u00fccudun de\u011fi\u015fik yerlerinde pap\u00fcl, vezik\u00fcl ve p\u00fcst\u00fcllerin birbirini takip ederek ortaya \u00e7\u0131kmas\u0131, hastal\u0131\u011f\u0131n tipik semptomu olarak kabul edilir.    14 g\u00fcn s\u00fcreyle her g\u00fcn CPE olu\u015fumu y\u00f6n\u00fcnden kontrolleri yap\u0131l\u0131r. Vir\u00fcs izolasyonu i\u00e7in al\u0131nan<\/p>\n\n\n\n

kan \u00f6rnekleri m\u00fcmk\u00fcn oldu\u011fu kadar \u00e7abuk ve buz i\u00e7inde ta\u015f\u0131nmal\u0131d\u0131r. Pratik olarak \u00f6rnekler +4\u00b0C de 2 g\u00fcn s\u00fcreyle l\u00f6kositler ayr\u0131larak inokulasyon yap\u0131l\u0131ncaya kadar muhafaza edilebilir. Uzun s\u00fcreli muhafaza i\u00e7in -20 \u00b0C kullan\u0131labilir. E\u011fer doku \u00f6rneklerinin al\u0131nd\u0131\u011f\u0131 yer uzak ise ve so\u011fuk zincir yok ise % 10 gliserol + fizyolojik tuzlu su veya fosfat buffer sol\u00fcsyonu veya vasat i\u00e7inde nakledilir ve vir\u00fcs izolasyonu i\u00e7in al\u0131nan biyopsi materyalinin merkezi k\u0131sm\u0131 kullan\u0131l\u0131r. Histopatolojik muayeneler i\u00e7in lezyonlu b\u00f6lgelerden al\u0131nan doku \u00f6rnekleri %10 formol solusyonu i\u00e7inde muhafaza edilir. Hastal\u0131\u011f\u0131n te\u015fhisinde serolojik testler aras\u0131nda en spesifik olan\u0131 serum n\u00f6tralizasyon testidir. Buna ek olarak agar jel immunodiffizyon, EL\u0130SA, \u0130FAT, FAT kullan\u0131labilir.<\/p>\n\n\n

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\"\"<\/a><\/figure>\n<\/div>\n\n\n

 Otopsi Bulgular\u0131:<\/strong><\/p>\n\n\n\n

   Deri lezyonlar\u0131nda s\u0131ras\u0131yla pap\u00fcl, vezik\u00fcl, p\u00fcst\u00fcl ve kabuk olu\u015fumu g\u00f6zlenir. Akci\u011ferlerde kataral pn\u00f6ymoni sahalar\u0131 g\u00f6r\u00fcl\u00fcr.Buralarda k\u00fc\u00e7\u00fck boz renkte kaze\u00f6z nod\u00fcller vard\u0131r. Bu odaklar\u0131n boyu 1-2 cm , ortalar\u0131 beyaz, mat ve balmumu renkli ve \u00e7evreleri k\u0131rm\u0131z\u0131d\u0131r. Karaci\u011fer ve b\u00f6breklerde de akci\u011ferdekine benzer lezyonlara rastlan\u0131r. Sindirim kanal\u0131 mukozalar\u0131nda hemorajik yang\u0131lar g\u00f6zlenir.<\/p>\n\n\n\n

Tedavi: <\/strong>Kesin tedavisi yoktur. Semptomatik tedavi yap\u0131l\u0131r.<\/p>\n\n\n\n

 Korunma:<\/strong><\/p>\n\n\n\n

   Hayvanlar\u0131 koyun \u00e7i\u00e7e\u011fine kar\u015f\u0131 korumada canl\u0131 ve inaktif a\u015f\u0131lardan yararlan\u0131lmaktad\u0131r. Canl\u0131 A\u015f\u0131 koruyucu ama\u00e7la sonbahar mevsiminin ba\u015flar\u0131nda , hastal\u0131k \u00e7\u0131kan b\u00f6lgelerde hastal\u0131\u011f\u0131 takiben iki y\u0131l boyunca y\u0131lda bir kez sa\u011flam s\u00fcr\u00fclerde 6-12 haftal\u0131k kuzu ve o\u011flaklara 0.2 ml ve 12 haftal\u0131ktan b\u00fcy\u00fcklere 0.5 ml verilir. 6 haftal\u0131ktan k\u00fc\u00e7\u00fck kuzu ve o\u011flaklara uygulanmaz. A\u015f\u0131 koyun ve ke\u00e7ilerin gebeliklerinin son 6 haftas\u0131nda ve do\u011fumdan sonraki ilk ayda hastal\u0131k \u00e7\u0131kmayan yerlerde koruyucu ama\u00e7la yap\u0131lmamal\u0131d\u0131r. A\u015f\u0131n\u0131n uygulama yeri; koyun ve kuzularda koltuk alt\u0131 y\u00fcns\u00fcz b\u00f6lge, ke\u00e7i ve o\u011flaklarda kuyrukta deri alt\u0131 uygulan\u0131r. Ba\u011f\u0131\u015f\u0131kl\u0131k 21 g\u00fcnde tam olarak olu\u015fur, ba\u011f\u0131\u015f\u0131kl\u0131k s\u00fcresi 8 ayd\u0131r.<\/p>\n\n\n\n

   Hastal\u0131k ile m\u00fccadelede en \u00f6nemli nokta sa\u011fl\u0131kl\u0131 s\u00fcr\u00fclere koyun ke\u00e7i \u00e7i\u00e7e\u011fine yakalanm\u0131\u015f hayvan sokmamakt\u0131r. Bu ama\u00e7la d\u0131\u015far\u0131dan sat\u0131n al\u0131nan koyun ve ke\u00e7iler en az 21 g\u00fcn s\u00fcre ile karantina alt\u0131nda ayr\u0131 bir yerde bar\u0131nd\u0131r\u0131lmal\u0131 ve bu s\u00fcre sonunda e\u011fer hayvanlarda hastal\u0131k belirtisi g\u00f6r\u00fclmezse hayvanlar sa\u011fl\u0131kl\u0131 s\u00fcr\u00fcye kat\u0131lmal\u0131d\u0131r.  \u00d6len hayanlar derin \u00e7ukurlara kire\u00e7 d\u00f6k\u00fclerek g\u00f6m\u00fclmeli ve hasta hayvanlar\u0131n bulunduklar\u0131 a\u011f\u0131llar dezenfekte edilmelidir. Hasta hayvanlar ile temasta bulunan ki\u015filer kesinlikle sa\u011fl\u0131kl\u0131 hayvanlar ile temas etmemelidir.<\/p>\n\n\n

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\"\"<\/a><\/figure>\n<\/div>\n\n\n

 Hayvan sa\u011fl\u0131\u011f\u0131 ve Zab\u0131tas\u0131 Y\u00f6netmeli\u011finde Koyun-Ke\u00e7i \u00c7i\u00e7e\u011fi hastal\u0131\u011f\u0131 hakk\u0131nda Mevzuat:<\/strong><\/p>\n\n\n\n

    Madde 111- Yurt i\u00e7inde koyun ve ke\u00e7ilerde \u00e7i\u00e7ek hastal\u0131\u011f\u0131n\u0131n \u00e7\u0131kt\u0131\u011f\u0131n\u0131 haber alan h\u00fck\u00fcmet veteriner hekimi hastal\u0131k mahalline gelince hasta hayvanlar\u0131 muayene eder ve hastal\u0131k raporunu d\u00fczenler. Hayvan sa\u011fl\u0131k zab\u0131tas\u0131 komisyonu hastal\u0131k \u00e7\u0131k\u0131\u015f karar\u0131n\u0131 al\u0131r ve hastal\u0131\u011f\u0131 ilan eder.<\/p>\n\n\n\n

    \n
  1. \u00c7i\u00e7ek hastal\u0131\u011f\u0131na yakalanm\u0131\u015f koyun ve ke\u00e7iler ayr\u0131 bir yerde muhafaza alt\u0131na al\u0131n\u0131r. Hastal\u0131ktan \u015f\u00fcpheliler m\u00fc\u015fahede alt\u0131nda tutulur. Hastal\u0131\u011f\u0131n bula\u015fmas\u0131 tehlikesi olan b\u00fct\u00fcn koyun ve ke\u00e7ilere \u00e7i\u00e7ek a\u015f\u0131s\u0131 uygulan\u0131r.<\/li>\n\n\n\n
  2. \u00c7i\u00e7ek hastal\u0131\u011f\u0131ndan veya hastal\u0131k \u015f\u00fcphesi alt\u0131ndaki hayvanlardan \u00f6lenler derileri ile birlikte yak\u0131larak yahut derin \u00e7ukurlara g\u00f6m\u00fclmek suretiyle imha edilir.<\/li>\n\n\n\n
  3. Karantina b\u00f6lgesine d\u0131\u015far\u0131dan hayvan girmesine ve i\u00e7eriden hayvan \u00e7\u0131kar\u0131lmas\u0131na izin verilmez. Karantina kald\u0131r\u0131l\u0131ncaya kadar buradaki hayvanlar, y\u00fcn ve derileri, hayvan yemleri ve maddeleri ile s\u00fcr\u00fc k\u00f6peklerinin d\u0131\u015far\u0131 \u00e7\u0131kar\u0131lmas\u0131 yasaklan\u0131r.<\/li>\n\n\n\n
  4. Hastal\u0131kl\u0131 veya hastal\u0131ktan \u015f\u00fcpheli hayvanlarda kullan\u0131lan her t\u00fcrl\u00fc alet ve malzeme dezenfekte edildikten sonra karantina b\u00f6lgesi d\u0131\u015f\u0131na \u00e7\u0131kar\u0131lmas\u0131na m\u00fcsaade edilir.<\/li>\n\n\n\n
  5. Karantinaya al\u0131nan yerlerdeki hastal\u0131ktan ve bula\u015fmadan \u015f\u00fcpheliler ile iyile\u015fmi\u015f hayvanlar\u0131n kapal\u0131 vas\u0131talarla en yak\u0131n mezbahada kesilmelerine izin verilir. Bula\u015fmadan \u015f\u00fcpheli hayvanlar\u0131n y\u00fcn, deri, t\u0131rnak ve boynuzlar\u0131n\u0131n dezenfekte edilmesi zorunludur.<\/li>\n\n\n\n
  6. Hastal\u0131k \u00e7\u0131kan yerlerdeki koyun ve ke\u00e7ilerin 10 g\u00fcn i\u00e7inde kesilecekleri tespit edilmi\u015fse bu hayvanlara a\u015f\u0131 uygulanmaz.<\/li>\n\n\n\n
  7. Hastal\u0131kl\u0131 yerden izinsiz olarak \u00e7\u0131kar\u0131lan s\u00fcr\u00fcler bulundu\u011fu yerde karantinaya al\u0131n\u0131r. \u00c7\u0131karanlar hakk\u0131nda kanuni i\u015flem yap\u0131lmak \u00fczere savc\u0131l\u0131\u011fa m\u00fcracaat edilir.<\/li>\n\n\n\n
  8. \u00c7i\u00e7ek hastal\u0131\u011f\u0131na yakalanm\u0131\u015f hayvanlarda iyile\u015fenler 15 g\u00fcn bekletildikten sonra dezenfekte edilerek hastal\u0131ks\u0131z hayvanlar\u0131n yan\u0131na g\u00f6nderilir.<\/li>\n\n\n\n
  9. Koyun veya ke\u00e7i \u00e7i\u00e7ek hastal\u0131\u011f\u0131na yakalanm\u0131\u015f hayvanlar\u0131n bulunduklar\u0131 yerlere giren bak\u0131c\u0131lar\u0131n \u00e7\u0131k\u0131\u015flar\u0131nda gerekli dezenfeksiyonu yapmalar\u0131 zorunludur.<\/li>\n\n\n\n
  10. Hastal\u0131k \u00e7\u0131kan yerlerdeki hayvan yemlerinin buradaki hayvanlar taraf\u0131ndan t\u00fcketilmesine m\u00fcsaade edilir.<\/li>\n\n\n\n
  11. Koyun veya ke\u00e7i \u00e7i\u00e7ek hastal\u0131\u011f\u0131 sebebiyle al\u0131nan karantina tedbirleri son iyile\u015fme veya \u00f6l\u00fcmden 60 g\u00fcn sonra kald\u0131r\u0131l\u0131r.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Koyun-ke\u00e7i \u00e7i\u00e7e\u011fi, koyun ve ke\u00e7ilerde ate\u015f, \u00f6zelikle deri ve akci\u011ferlerde olmak \u00fczere hayvanlar\u0131n b\u00fct\u00fcn v\u00fccuduna yay\u0131lan, vezik\u00fcllerle (i\u00e7i s\u0131v\u0131 dolu kesecikler) karakterize \u00f6ld\u00fcr\u00fcc\u00fc bir viral bir hastal\u0131\u011f\u0131d\u0131r.  Etiyolojisi: Hastal\u0131\u011f\u0131n etkeni bir vir\u00fcst\u00fcr. Vir\u00fcs Poxviridae familyas\u0131 Capripoxvirus genusunun bir \u00fcyesidir.Virus, \u00e7\u00fcr\u00fcmeye, asit ve alkali ko\u015fullara diren\u00e7lidir. Kuru kabuklarda y\u0131llarca, y\u00fcnde 2 ay ve bula\u015f\u0131k y\u00fczeylerde 6 […]<\/p>\n","protected":false},"author":5,"featured_media":2632,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,11,13,413,84],"tags":[580,581,583,584,582],"class_list":["post-2628","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hasta","category-keci","category-koyun","category-kucukbas","category-slider","tag-cicek","tag-pox","tag-sheep","tag-sisease","tag-virus"],"_links":{"self":[{"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/posts\/2628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/veteriner.cc\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2628"}],"version-history":[{"count":1,"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/posts\/2628\/revisions"}],"predecessor-version":[{"id":2633,"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/posts\/2628\/revisions\/2633"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/veteriner.cc\/index.php?rest_route=\/wp\/v2\/media\/2632"}],"wp:attachment":[{"href":"https:\/\/veteriner.cc\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/veteriner.cc\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/veteriner.cc\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}